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Correlation between IGF-1 and prognosis of patients with chronic disturbance of consciousness

Association between IGF-1 and prognosis in patients with chronic disorders of consciousness: a single-center prospective cohort study

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200058081
Enrollment
Unknown
Registered
2022-03-29
Start date
2022-03-21
Completion date
Unknown
Last updated
2023-12-03

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

chronic disturbance of consciousness

Interventions

case series:None

Sponsors

Shengjing Hospital Affiliated to China Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-65 years; 2. Patients with chronic disorders of consciousness: CRS-R diagnosis; 3. When the patient's family members signed the informed consent and entered the screening period, the course of the disease was greater than or equal to 3 months; 4. The patient's family is willing and able to cooperate with the scheduled visit, treatment plan and laboratory testing, and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Hba1c >9.0% at screening; 2. Seizures within a month; 3. Systolic blood pressure of less than 90mmHg or/and diastolic blood pressure of less than 50mmHg; 4. History of islet tumor or/and pheochromocytoma; 5. Patients with severe liver, kidney or cardiovascular diseases; 6. Patients who have participated in other drug clinical trials within 3 months; 7. A history of allergy to glucagon or insulin-like products, or a history of apparent allergy to other ingredients in the study preparation; 8. History of glycogen accumulation; 9. Used growth hormone therapy in the past one year; 10. Other reasons considered by the researcher to be excluded.

Design outcomes

Primary

MeasureTime frame
Glasgow Prognostic Scale (GOS);Modified Barthel Scale Score;

Countries

China

Contacts

Public ContactZhou Xiaolan
zhouxiaolanlan@163.com+86 18940259830

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026