facial dependent dermatitis
Conditions
Interventions
Control group:Clarithromycin for 3-4 weeks + Fexofenadine hydrochloride tablets for 8 weeks + 5-dimensional lysine granules for 12 weeks + normal saline wet compress
Observation group 1:Oral hydroxychloroquine sulfate tablets for 8 weeks
Observation group 2:Oral low dose isotretinoic acid for 8 weeks
Sponsors
Second Affiliated Hospital of Xi'an Jiaotong University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Aged over 18 years, no gender limit, willing to receive treatment, able to strictly abide by the treatment plan, signed informed consent; 2. Meet the diagnostic criteria for facial hormone-dependent dermatitis; 3. In addition to meeting the above conditions, patients receiving hydroxychloroquine sulfate should also be free from allergies and contraindications to hydroxychloroquine sulfate; No eye disease; 4. Patients receiving isotretinoic acid treatment should also meet the requirements of no allergy and contraindications to isotretinoic acid drugs, and no pregnancy plan within six months after drug withdrawal.
Exclusion criteria
Exclusion criteria: 1. Have used immunosuppressive agents (including hormones) or are receiving immunosuppressive agents (including hormones) within 3 months; 2. History of sun exposure within 1 month; 3. Photosensitive skin or use photosensitizer; 4. Suffering from seborrheic dermatitis, rosette acne, acne; 5. Have serious heart, liver and kidney diseases; 6. Pregnant and lactating patients; 7. High expectations; 8. Poor compliance.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Index of efficacy; | — |
Countries
China
Contacts
Public ContactLiu Ping
Second Affiliated Hospital of Xi'an Jiaotong University
Outcome results
None listed