Wound infection after spinal surgery
Conditions
Interventions
Experimental group:On the basis of routine anti infection treatment, vancomycin powder was applied to the wound during operation
Control group:Routine anti infection treatment
Sponsors
Beijing Chaoyang Hospital Affiliated to Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 18-70, gender unlimited; 2. Consistent with the indications for posterior spinal surgery; 3. All patients had signed informed consent prior to inclusion, and were aware of and agreed to the study content; 4. Regular follow-up is acceptable for at least 1 year.
Exclusion criteria
Exclusion criteria: 1. Patients with abnormal liver and kidney function; 2. Cefuroxime or vancomycin allergy; 3. Recent history of glucocorticoid use; 4. Complicated with local or systemic infectious diseases; 5. Patients with mental disorders, alcohol dependence and a history of drug abuse; 6. Patients who are breastfeeding or pregnant; 7. Patients with hearing abnormalities.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of wound infection one month after operation; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative infection index;Standard rate of blood vancomycin concentration;Fusion rate of surgical segmental bone graft; | — |
Countries
China
Contacts
Public ContactLu Hongyi
Outcome results
None listed