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Clinical efficacy of xenogenic collagen matrix apply to keratinized gingival augmentation around dental implants in mandibular posterior area

Clinical efficacy of xenogenic collagen matrix apply to keratinized gingival augmentation around dental implants in mandibular posterior area

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200058027
Enrollment
Unknown
Registered
2022-03-27
Start date
2022-03-16
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

dentition defect

Interventions

Heterogeneous collagen matrix group:xenogenic collagen matrix apply to keratinized gingival augmentation
Free gingival transplantation group:free gingival graft apply to keratinized gingival augmentation
Root - oriented reset flap group:apically positioned flap apply to keratinized gingival augmentation

Sponsors

Tianjin Stomatological Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Aged over 18 years. 2. The patient can cooperate with and tolerate the implantation process without serious systemic diseases. 3. Mandibular posterior teeth are missing, and buccal keratinized gingival is less than 2mm. 4. Good oral hygiene, healthy periodontal tissues, plaque index <=20% (Full-mouth plaque score, FMPS). 5. No severe night bruxism or smoking (<=10 teeth/day).

Exclusion criteria

Exclusion criteria: 1. Uncontrolled diabetes and high blood pressure. 2. Pregnant or breastfeeding patients. 3. Taking intravenous or bisphosphonates or long-term anticoagulant drugs. 4. Patients fail to return to the doctor on time and fail to follow the treatment procedures associated with the study.

Design outcomes

Primary

MeasureTime frame
buccal keratinized gingival width;keratinized gingival thickness;keratinized gingival width contraction;

Secondary

MeasureTime frame
periodontal index;aesthetic effect of operation area;

Countries

China

Contacts

Public ContactWang Yanying
qiuxiaohai@mail.nankai.edu.cn+86 18698128975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 12, 2026