Allergic rhinitis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1)Compliance with the diagnostic criteria in the ' Diagnosis and Guidelines for Allergic Rhinitis ' developed by the Department of Otolaryngology Head and Neck Surgery of the Chinese Medical Association in 2016; 2)Criteria for drug-resistant allergic rhinitis : patients whose symptoms could not be controlled after 4 - week treatment with nasal spray hormone combined with antihistamine drugs; 3)Tolerance of Pulsed Radiofrequency Therapy for Sphenopalatine Ganglion; 4)ASA?-?; 5)Age 18-60; 6)Patients signed informed consent.
Exclusion criteria
Exclusion criteria: 1 ) Pregnant or lactating, menstrual women, women planning to become pregnant within 3 months ; 2 ) Patients who received other treatment or oral, topical glucocorticoid, antihistamine and immunotherapy within four weeks before treatment ; 3 ) Congenital nasal deformity, sinus disease, severe nasal septum deviation and nasal polyps ; 4 ) combined with other refractory diseases such as specific dermatitis or a history of parasitic infection ; 5 ) patients with severe cardiovascular and cerebrovascular diseases, liver and kidney blood system diseases or malignant tumors, mental illness, diabetes, patients with bleeding tendency ; 6 ) Patients with pacemaker, defibrillator, artificial joint, contraceptive ring, etc. Because magnetic resonance imaging is performed in a narrow barrel environment, subjects with claustrophobia cannot participate in the test ; 7 ) Patients who failed to sign informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| TNSS;signs indexes;RQLQ;fMRI; | — |
Secondary
| Measure | Time frame |
|---|---|
| IgE;substance-P; | — |
Countries
China