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To explore the effect of Zishen Quyu Jiedu Recipe on the outcome of IVF-ET in patients with endometriosis of kidney deficiency and blood stasis type based on Wnt signal pathway

A Chinese Medical Syndrome Study of infertility due to phlegm dampness type PCOS based on follicular fluid proteomics

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057987
Enrollment
Unknown
Registered
2022-03-25
Start date
2022-04-15
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Endometriosis

Interventions

Patients with endometriosis of kidney deficiency and blood stasis type:Shishen Quyu detoxifying granules
Patients with endometriosis of kidney deficiency and blood stasis type:Placebo
Male factor patients:Placebo

Sponsors

Affiliated Hospital of Shandong University of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 40 Years

Inclusion criteria

Inclusion criteria: 1. Meets the diagnostic criteria of Chinese and Western medicine in this disease; 2. 20 <= age <= 40 years; 3. No use of hormonal agents in the three months before treatment; 4. Signed informed consent was obtained; 5. Approved by the ethics committee; 6. Conformed to the code of human assisted reproductive technology.

Exclusion criteria

Exclusion criteria: 1. Those who do not follow medical advice or are allergic to the ingredients of this traditional Chinese Medicine; 2. Combined poor ovarian reserve, ovarian neoplasms, PCOS, pelvic inflammatory disease and other systemic diseases affecting ovarian function; 3. Infertility due to genetic factors; 4. History of recurrent miscarriage; 5. Abnormal anatomy of the female genital tract precludes pregnancy; 6. Women with severe somatic or psychiatric illness not withstanding pregnancy.

Design outcomes

Primary

MeasureTime frame
siah2;wnt5a;ß-catenin;caspase3;CA125;

Secondary

MeasureTime frame
Number of eggs obtained;fertilization rate;Number of embryos;Excellent embryo rate;Clinical pregnancy rate;

Countries

China

Contacts

Public ContactLian Fang

Affiliated Hospital of Shandong University of Traditional Chinese Medicine

lianfangbangong@163.com+86 13706403122

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026