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Effect of percutaneous acupoint electrical stimulation combined with endovascular physiotherapy on endometrial receptivity and S100A11 expression during freeze-thawing embryo transfer period in patients with thin endometrium with kidney-yang deficiency

Study on TCM Syndrome of Phlegm-Dampness PCOS Infertility Based on Follicular Fluid Proteomics

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057985
Enrollment
Unknown
Registered
2022-03-25
Start date
2022-04-22
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Thin endometrium

Interventions

Therapy Group:Cavity therapy

Sponsors

Shandong Hospital of Traditional Chinese Medicine
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
25 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. The transplantation cycle was cancelled when the endometrial thickness was less than 7mm for two consecutive times; 2. Aged between 25 and 35; 3. Normal basal hormone levels; 4. Normal menstrual cycle and ovulation monitored by multi-cycle B-mode ultrasound; 5. No history of intrauterine operation in the past two months; 6. At least one high-quality embryo of grade II or above in the freeze-thaw embryo transfer cycle.

Exclusion criteria

Exclusion criteria: 1. Abnormal reproductive endocrine; Polycystic ovary syndrome, endometriosis, etc.; 2. Abnormal anatomical structure of the female reproductive tract does not have pregnancy function; 3. Severe hydrocephalus of fallopian tubes; 4. Other factors affecting the endometrial microenvironment (endometrial polyps, endometritis, adenomyosis, etc.); 5. If the woman is suffering from serious physical or mental disease and cannot conceive; 6. Those who failed to carry out embryo transplantation due to various reasons during the treatment.

Design outcomes

Primary

MeasureTime frame
S100A11;Endometrial artery blood flow;Endometial thickness;The type of endometrium;Cycle cancellation rate;Rate of biochemical pregnancy;Rate of pregnancy;

Countries

China

Contacts

Public ContactLian Fang

Affiliated Hospital of Shandong University of Traditional Chinese Medicine

lianfangbangong@163.com+86 13706403122

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026