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Neuroimaging mechanisms of benzodiazepines dependence in sleep disorders

Neuroimaging mechanisms of benzodiazepines dependence in sleep disorders

Status
Recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057967
Enrollment
Unknown
Registered
2022-03-24
Start date
2022-03-23
Completion date
Unknown
Last updated
2023-11-27

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Benzodiazepines dependence

Interventions

None listed

Sponsors

The First Affiliated Hospital of University of South China
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Have a healthy past, meet the DSM-V criteria for substance use disorder, suffer from anxiety, depression, or sleep disorders, have no other mental illness, and have no history of psychotropic drug use; 2. Patients aged 18-65 years old, and the age distribution of the selected patients was roughly uniform (18-65); 3. Primary school education or above; 4. Informed consent signed by the patient or legal representative.

Exclusion criteria

Exclusion criteria: 1. History of neurological diseases (such as epilepsy, cerebrovascular accidents, etc.); 2. A long history of heavy alcohol consumption; 3. Breastfeeding/pregnant women; 4. Patients with MR Contraindications such as a cardiac pacemaker or other metal implants or space classtrophy; 5. The presence of major systemic diseases or unstable medical conditions (such as significant heart, liver, kidney, or lung dysfunction, severe diabetes, or blood system disorders, severe infections, mental illness, cancer, alcohol or drug abuse, etc.) may make it difficult to complete the experiment.

Design outcomes

Primary

MeasureTime frame
Brain MRI;Diagnostic and Statistical Manual of Mental Disorders;International Classification of Diseases;Mini-mental State Examination;Montreal Cognitive Assessment;

Countries

China

Contacts

Public ContactZhou Hong

The First Affiliated Hospital of University of South China

zhouhong@msn.cn+86 18607340315

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026