Type 2 diabetes mellitus
Conditions
Interventions
Obsevation group 1:Any antiglycemic drugs except glucagon-like peptide-1 receptor agonists
Observation group 2:Glucagon-like peptide-1 receptor agonists
Control group:None
Sponsors
The Second People's Hospital of Huai 'an
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Type 2 diabetes population: (1) Type 2 diabetes mellitus (1999 WHO diagnostic criteria); (2) 18=18.5; (4) With no previous treatment history of glucagon-like peptide-1 receptor agonists. 2. Healthy population: (1) 18<=age<=65 years old; (2) 18.5<= BMI <24.0, abdominal circumference:male <85cm, female <80cm; (3) Fasting blood glucose <7.0 mmol/L, or random blood glucose <11.1mmol/L.
Exclusion criteria
Exclusion criteria: 1. Other types of diabetes mellitus; 2. People with acute disease or chronic disease with acute complications (such as myocardial infarction, acute cerebral infarction; acute liver failure; DKA, etc.); 3. People with any malignant disease; 4. People with clear etiology of fatty liver: such as alcoholic fatty liver, viral fatty liver, etc.; 5. People cannot tolerate glucagon-like peptide-1 receptor agonists.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Istnmin-1;blood glucose concentration;Blood C-peptide concentration;Glycosylated hemoglobin;Total cholesterol;Triglyceride concentration;High density lipoprotein cholesterol;Low density lipoprotein cholesterol; | — |
Secondary
| Measure | Time frame |
|---|---|
| Blood creatinine concentration;Blood creatinine concentration;Urinary albumin creatinine ratio;homocysteine concentration;Blood urea concentration;clinical characteristic; | — |
Countries
China
Contacts
Public ContactBai feng
The Second People's Hospital of Huai 'an
Outcome results
None listed