Mandibular Impacted Third Molar
Conditions
Interventions
Test group:One Ibuprofen Sustained-Release Capsule will be taken orally 15 minutes before operation
Sponsors
Beijing Stomatological Hospital, Capital Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 50 Years
Inclusion criteria
Inclusion criteria: 1. The age is between 18-50 years old; 2. No history of cardiopulmonary disease, liver and kidney disease, abnormal bleeding, and abnormal coagulation function; 3. No analgesic, anti-inflammatory, and anticoagulant drugs were taken 1 week before tooth extraction; 4. Mandibular median mesial impacted third molars in Pell and Gregory classification; 5. The operation is expected to be completed within 15-30 minutes; 6. Patients are willing to participate in this study and fill in the questionnaire.
Exclusion criteria
Exclusion criteria: 1. Pregnant, physiological or lactating women; 2. Combined with acute oral infectious diseases or tumors. 3. Allergic reaction to the drug used in this study; 4.Suffering from chronic pulpitis, chronic periapical periodontitis, trigeminal neuralgia, glossopharyngeal neuralgia and other pain diseases without treatment or requiring long-term use of other painkillers; 5. The patient drank alcohol within one week before operation; 6. Patients with previous history of upper gastrointestinal bleeding or perforation related to the use of nonsteroidal anti-inflammatory drugs; 7. Patients with active or previous history of peptic ulcer, gastrointestinal bleeding or perforation; 8. Allergic to other non steroidal anti-inflammatory drugs; 9. Asthmatic patients allergic to aspirin; 10. Taking other anti-inflammatory drugs containing ibuprofen or other non steroidal drugs, including drugs known to be specific cyclooxygenase-2 inhibitors; 11. Patients with intellectual, visual, hearing or communication impairment or other patients considered by the investigator to be unsuitable to participate in the trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score; | — |
Secondary
| Measure | Time frame |
|---|---|
| score of Dental Fear Survey (DFS);score of Stouthard's Dental Anxiety Inventory( DAI);Dosage and duration of postoperative analgesics;VAS score; | — |
Countries
China
Contacts
Public ContactZhou Jian
Beijing Stomatological Hospital, Capital Medical University
Outcome results
None listed