knee osteoarthritis
Conditions
Interventions
experimental group:Infusion of Sodium Bicarbonate Ringer's Injection
control group:Infusion of Sodium Lactate Ringer's Solution
Sponsors
Weifang Medical University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Age >= 40 years; 2. BMI: 20-30 kg/m2; 3. ASA grade was I to III; 4. No serious cardiovascular and cerebrovascular diseases, hypothyroidism, hypermagnesia, blood diseases and other basic diseases before surgery; 5. There was no open traumatic wound, edema, thromboangiitis, venous embolism or severe arteriosclerosis on the skin of the affected limb for more than 6 hours.
Exclusion criteria
Exclusion criteria: 1. Patients with severe intraoperative hemodynamic changes; 2. Patients with dramatic changes in intraoperative arterial blood gas analysis; 3. Patients who did not sign the informed consent.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Duration of tourniquet use;arterial blood pressure;heart rate;pulse perfusion index;pulse perfusion variance index;partial pressure of carbon dioxide;bicarbonate ion;base excess;sodion;potassium ion;calcium ion;blood glucose;lactic acid;hemoglobin;hematokrit;liquid input;awakening time;evacuation time;nausea and vomiting;postoperative cognitive function;length of stay; | — |
Secondary
| Measure | Time frame |
|---|---|
| height;weight;anesthesia time;intraoperative blood loss;intraoperative urinary volume;the amount of vasoactive drugs used; | — |
Countries
China
Contacts
Public ContactShijie Zhang
Weifang Medical University
Outcome results
None listed