Tuberculosis
Conditions
Interventions
Stage I pneumoconiosis:
Stage I pneumoconiosis/LTBI:
Stage II pneumoconiosis:
Stage II pneumoconiosis/LTBI:
Stage III pneumoconiosis:
Stage III pneumoconiosis/LTBI:
LTBI of Health control:
Health control:
Sponsors
Shenzhen Third People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Patients aged 18-80 years; 2. Inpatients diagnosed as stage I, II, III pneumoconiosis in the Occupational Disease Department of the Fourth Hospital of West China; 3. Those who have received physical examination in the Physical Examination Department of the Fourth Hospital of West China; 4. Participate voluntarily and have signed informed consent.
Exclusion criteria
Exclusion criteria: 1. Immunosuppressed patients; 2. Patients with a history of tuberculosis; 3. Patients who have received LTBI treatment; 4. HIV patients; 5. Diagnosed patients with active tuberculosis; 6. Previous history of mental illness or cognitive dysfunction; 7. Pregnant or lactating women; 8. Patients who cannot obtain clinical diagnosis due to short stay in hospital or complicated condition; 9. Other conditions deemed unsuitable for the study by the researcher.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Three genes (GBP5, DUSP3 and KLF2);Blood transcriptomics;Blood immunomics; | — |
Countries
China
Contacts
Public ContactShuihua Lu
Shenzhen Third People's Hospital
Outcome results
None listed