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Randomized controlled trial of real-time fluorescent visualization with indocyanine green in laparoscopic cholecystectomy: optimal indocyanine green dose exploration within preoperative 30 minutes

Clinical application of indocyanine green combined with near-infrared fluorescence imaging system in extrahepatic biliary tract surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057933
Enrollment
Unknown
Registered
2022-03-22
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Extrahepatic biliary cholelithiasis

Interventions

Group A:ICG dose: 0.025 mg/case
Group B:ICG dose: 0.1 mg/case
Group C:ICG dose: 0.1 mg/case
Group D:ICG dose: 2.5 mg/case

Sponsors

Guangzhou First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 95 Years

Inclusion criteria

Inclusion criteria: 1. Patients requiring laparoscopic cholecystectomy; 2. There is no biliary obstruction; 3. No changes of cirrhosis were reported by CT or B ultrasound; 4. Age >= 18 years; 5. Able to listen, speak, read and understand Chinese, able to understand the test requirements and willing to cooperate with the researchers in the test, and voluntarily sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with a history of iodine allergy; 2. Patients with allergies to ICG or a history of allergies.

Design outcomes

Primary

MeasureTime frame
Biliary fluorescence intensity value;liver fluorescence intensity value;

Secondary

MeasureTime frame
bile duct to liver ratio (BLR);

Countries

China

Contacts

Public ContactWeili Gu

Guangzhou First People's Hospital

lili-6423@163.com+86 15920583431

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 14, 2026