preoperative anxiety
Conditions
Interventions
Group R:remazolam before anesthesia induction
Group E:estazolam the night before surgery
Group RE:estazolam the night before surgery and remazolam before anesthesia induction
Group C:saline before anesthesia induction
Sponsors
Lianyungang First People's Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. Patients selected for laparoscopic cholecystectomy; 2. Aged 18-65; 3. Body mass index (BMI) 18 25kg/m2; 4. The American Association of Anesthesiologists (ASA) is classified as Grade I to Grade II; 5. The preoperative anxiety score (VAS-A) is greater than 0; 6. Those who voluntarily participate in this study and sign the relevant informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with oral history of sedative and analgesic drugs 14 days before surgery(benzodiazepines, barbiturates, non-steroidal anti-inflammatory drugs, opioid analgesics, etc.) ; 2. Patients with previous gastrointestinal dysfunction; 3. Patients with severe liver and kidney dysfunction; 4. Patients with contraindications or allergic reactions to benzodiazepine use; 5. Patients who cannot understand the meaning of the scoring scale and have difficulty in language communication; 6. Patients with a history of mental illness or disturbance of consciousness.
Design outcomes
Secondary
| Measure | Time frame |
|---|---|
| Incidence of postoperative nausea and vomiting;Sleep quality score after surgery;Ramsay sedation score after surgery;Patient satisfaction score; | — |
Primary
| Measure | Time frame |
|---|---|
| Time of first exhaust after surgery;Time of first defecation after surgery;I-FEED score; | — |
Countries
China
Contacts
Public ContactFeng Jiying
Lianyungang First People's Hospital
Outcome results
None listed