Type II respiratory failure
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age = 18 years; 2. Respiratory support is needed because of the admission of type II respiratory failure or type II respiratory failure during the course of the disease; 3.PaCO2>50mmHgPH>7.25
Exclusion criteria
Exclusion criteria: 1. Severe respiratory failure requires immediate tracheal intubation: RR>40 times/min, P/F<150 under severe hypoxia and high concentration oxygen inhalation, severe respiratory acid PH<7.25, consciousness disorder GCS<8, etc; 2. Those who have contraindications to HFNC or NIV treatment: oral and facial trauma, nasal obstruction, poor ability to discharge sputum due to excessive sputum, and severe instability of hemodynamics; 3. Patients with poor short-term prognosis and high risk of death within 7 days are undergoing palliative treatment; 4. Acute severe failure of other organs; 5. Tracheostomy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| partial pressure of carbon dioxide; | — |
Secondary
| Measure | Time frame |
|---|---|
| pH value;arterial partial pressure of oxygen;respiratory rate;Heart Rate;Blood Pressure;Rate of tracheal intubation;Treatment mode conversion;Respiratory support time;Comfort and tolerance rating;Length of ICU stay;Total length of stay;28-day case fatality rate; | — |
Countries
China
Contacts
Northern Jiangsu People's Hospital