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Effects of propofol and sevoflurane on early postoperative gastrointestinal motility in patients undergoing laparoscopic gynecological surgery

Effects of propofol and sevoflurane on early postoperative gastrointestinal motility in patients undergoing laparoscopic gynecological surgery

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057874
Enrollment
Unknown
Registered
2022-03-20
Start date
2022-04-01
Completion date
Unknown
Last updated
2023-11-21

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

General anesthesia/Gynecological disease

Interventions

SEV group:Inhalation of sevoflurane to maintain anesthesia
TIVA group:Infusion of propofol to maintain anesthesia

Sponsors

Affiliated Hospital of Yan'an University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
19 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. ASA grade I II, age 19 60, BMI 18.5 28.0kg/m2; 2. The estimated pneumoperitoneum time is 1-3 hours; 3. No abuse of hormone drugs or psychotropic drugs for a long time in the past; 4. No previous history of abdominal surgery or gastrointestinal diseases.

Exclusion criteria

Exclusion criteria: 1. Simultaneous operation with abdominal organs; 2. The operation was converted to laparotomy; 3. The patient and his family disagreed, and the follow-up data was incomplete, so he withdrew from the survey halfway.

Design outcomes

Primary

MeasureTime frame
Gastric emptying ratio;Ampliude of gastric antrum contraction;antral contraction frequency;gastric motility index;incidence of abdominal pain,abdominal distension and diarrhea;

Secondary

MeasureTime frame
bowel sound reccovery time;first anal exhaust time;first eating time;incidence of nausea and vomiting;pneumoperitoneum time;anesthesia time;opioid dosage;Intraoperative infusion volume;Intraoperative bleeding;Time of the first ambulatory session after surgery;length of stay;Urinary tube lien time;Mean arterial pressure and heart rate;Pain VAS score;Operation time;

Countries

China

Contacts

Public ContactErfei Zhang

Affiliated Hospital of Yan'an University

zhangerfei09@126.com+86 13891170975

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026