Spinal anesthesia/Osteoarthritis of the knee
Conditions
Interventions
A group:(22.0-25.0 ?)1% ropivacaine 1ml (10 mg)
B group:(22.0-25.0?) 1% ropivacaine 0.5ml (5mg)
C group:(36.0-37.5?) 1% ropivacaine 0.5ml (5mg)
Sponsors
Affiliated Hospital of Yan 'an University
Eligibility
Sex/Gender
All
Age
55 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Aged 55-75 years, ASA grade < III, BMI < 30Kg/m2; 2. No serious heart, cerebrovascular, liver or kidney diseases; 3. Muscle strength of lower limbs was normal before surgery; Daily life score expression 6 points; 4. No contraindications of intraspinal puncture.
Exclusion criteria
Exclusion criteria: 1.Abnormal mental state during operation; 2.Patients with intraoperative change of general anesthesia; 3.Emergency surgery due to complications after surgery; 4.The operation lasted longer than 2.5 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Proportion of patients walking out of bed in early stage (walking for 5 minutes within 1 to 1.5 hours after surgery);Duration of anesthesia; | — |
Secondary
| Measure | Time frame |
|---|---|
| Time of onset of anesthesia;Highest level of arrest;Unilateral limb block rate;Onset time of motor block;Muscle strength measurement criteria;Peel waiting time;Liquid in and out;Number of vasoactive drugs used;The length of time;Active functional exercise times of affected limbs within 12 hours after operation;Catheter indwelling time;Opioid use;Postoperative analgesic VAS score at 3d;The number of active turning in bed within 8 hours after surgery;Active functional exercise times of affected limb within 6 hours after operation;Incidence of nausea and vomiting within 2 days after operation;Blood pressure;Heart rate;Intraoperative muscle relaxation score;The operation time;The incidence of postoperative cardiovascular complications; | — |
Countries
China
Contacts
Public ContactEr-Fei Zhang
Affiliated Hospital of Yan 'an University
Outcome results
None listed