Depression
Conditions
Interventions
Cognitive training group (adult):VR-based cognitive training
EMDR group (adult):VR-based EMDR
Cognitive training group (children&adolescent):VR-based cognitive training
Cognitive training&EMDR group (children & adolescent):VR-based cognitive training+VR-based EMDR
Control group(adult):Treatment as usal
Control group(children&adolescent):Treatment as usal
EMDR group(children&adolescent) :VR-based EMDR
CCRT group:CCRT intervention
Sponsors
First Affiliated Hospital of Jinan University
Eligibility
Sex/Gender
All
Age
10 Years to 45 Years
Inclusion criteria
Inclusion criteria: 1. Participants diagnosed as major depressive disorder or bipolar depression according to the Diagnostic and statistical manual of mental disorders, Fifth edition (DSM-5); 2. Aged 10-45 years old; 3. Normal vision and right-handed; 4. Have not received an MCCB or DN-CAS cognitive assessment before enrollment; 5. Volunteer to participate in this study.
Exclusion criteria
Exclusion criteria: 1. Other Axis I psychiatric disorders and symptoms; 2. A history of the use of electroconvulsive therapy; 3. High risk of suicide; 4. A history of neurological or organic brain disorder; 5. A history of alcohol/substance abuse; 6. Any physical illness demonstrated by personal history or clinical or laboratory examinations, pregnancy, or postpartum depression; 7. Virtual reality sickness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hamilton depression scale,HAMD;Hamilton Anxiety Scale, HAMA;Young Mania Rating Scale ,YMRS;Patient Health Questionnaire-9, PHQ-9;Generalized Anxiety Disorder, GAD-7;Hypomania Check List,HCL-32;Childhood Trauma Questionnaire,CTQ;PTSD CheckList-Civilian Version, PCL-C;Massachusetts General Hospital Cognitive and Physical Functioning Questionnaire,CPFQ;MATRICS Consensus Cognitive Battery,MCCB;Beck Scale for Suicide Ideation,BSSI;Das-Naglieri:Cognitive Assessment System,DN:CAS;Rejection Sensitivity Questionnaire,RSQ;Emotional Intelligence Scale,EIS;Adolescents Self-injury Scale,ASIS;Resilience Scale for Chinese Adolescents,RSCA;Perceived Social Support Scale,PSSS;Fam-ily Assessment Device,FAD;Adolent Self-Rating Life Events Check List,ASLEC;Columbia-Sui-Severity Rating Scale, C-SSRS;NAA/Cr ratios of prefrontal cortex;NAA/Cr ratios of basal ganglia;NAA/Cr ratios of cerebellum;mI/Cr ratios of prefrontal cortex;mI/Cr ratios of basal ganglia;mI/Cr ratios of cerebellum;Cho/Cr ratios of prefrontal cortex;Cho/Cr ratios of basal ganglia;Cho/Cr ratios of cerebellum; | — |
Countries
China
Contacts
Public ContactYanbin Jia
First Affiliated Hospital of Jinan University
Outcome results
None listed