lymphedema
Conditions
Interventions
Treatment group:Acrolimus
Sponsors
Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 18-75 years old, gender is not limited; 2. Understand the purpose of the research and sign the informed consent voluntarily; 3. Clinically diagnosed with lymphedema and the cumulative body surface area is less than 15%; 4. International stage of lymphedema I-II.
Exclusion criteria
Exclusion criteria: 1. Pregnant, breastfeeding, or trying to conceive; 2. Known allergy to tacrolimus or other macrolides; 3. Suffering from mental illness that may affect participation in the project; 4. Reduced kidney or liver function; 5. Defective skin barrier; 6. Diagnosed immunodeficiency; 7. Patients who are judged by the investigator to be unsuitable to participate in this experiment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Volume of affected area; | — |
Secondary
| Measure | Time frame |
|---|---|
| Frequency of skin infections such as cellulitis or erysipelas;Lymphedema Functional Score and Quality of Life Questionnaire;Lymphonuclide angiography;The number of CD4+T cells, CD8+T cells and Th cell subsets were measured in serum; | — |
Countries
China
Contacts
Public ContactDeng Chengliang
Affiliated Hospital of Zunyi Medical University
Outcome results
None listed