Metabolic and Cardiovascular disease
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Healthy adults aged 18-35 y; 2. Body mass index in the range of 18.0-28.0 kg/m2; 3. Stable weight (change <+-3%) for 3 months prior to the study; 4. Healthy lifestyle with regular eating, sleep and exercise patterns; 5. No medications within 3 months prior to the study; 6. No acute and chronic diseases as determined by medical history, physical examination, and laboratory tests. Including diabetes, hyperlipidemia, and hypertension; 7. No caffeine or alcohol intake habit; 8. No use of tobacco; 9. Able to sign consent independently.
Exclusion criteria
Exclusion criteria: 1. Shift work or jet lag within a month and during the experiment; 2. Antibiotics were applied in the last 3 months; 3. Diseases with abnormal clinical manifestations that need to be excluded, including but not limited to nervous system, cardiovascular system, blood, lymphatic system, respiratory system, digestive system, urinary system, immune system, kidney, liver or metabolic disorders, or mental system diseases; 4. Pregnant or breast-feeding; 5. Insomnia; 6. Participants in other experiments within the last 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Energy metabolism;Heart rate;Blood glucose;Blood presure; | — |
Secondary
| Measure | Time frame |
|---|---|
| Oxygen saturation;Respiration rate;Endocrine hormones;Blood gas;Visual analog scale;Respiratory quotient; | — |
Countries
China
Contacts
Ruijin Hospital, Shanghai Jiaotong University, School of Medicine