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Effect of N95 Face Masks on Human Metabolism: A Randomized Cross-Over Clinical Trial

Effect of N95 Face Masks on Human Metabolism: A Randomized Cross-Over Clinical Trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057813
Enrollment
Unknown
Registered
2022-03-17
Start date
2022-03-07
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metabolic and Cardiovascular disease

Interventions

Wearing face mask:Wearing N95 face mask
Without wearing face mask :Without wearing N95 face mask

Sponsors

Ruijin Hospital, Shanghai Jiaotong University School of Medicine
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
18 Years to 35 Years

Inclusion criteria

Inclusion criteria: 1. Healthy adults aged 18-35 y; 2. Body mass index in the range of 18.0-28.0 kg/m2; 3. Stable weight (change <+-3%) for 3 months prior to the study; 4. Healthy lifestyle with regular eating, sleep and exercise patterns; 5. No medications within 3 months prior to the study; 6. No acute and chronic diseases as determined by medical history, physical examination, and laboratory tests. Including diabetes, hyperlipidemia, and hypertension; 7. No caffeine or alcohol intake habit; 8. No use of tobacco; 9. Able to sign consent independently.

Exclusion criteria

Exclusion criteria: 1. Shift work or jet lag within a month and during the experiment; 2. Antibiotics were applied in the last 3 months; 3. Diseases with abnormal clinical manifestations that need to be excluded, including but not limited to nervous system, cardiovascular system, blood, lymphatic system, respiratory system, digestive system, urinary system, immune system, kidney, liver or metabolic disorders, or mental system diseases; 4. Pregnant or breast-feeding; 5. Insomnia; 6. Participants in other experiments within the last 3 months.

Design outcomes

Primary

MeasureTime frame
Energy metabolism;Heart rate;Blood glucose;Blood presure;

Secondary

MeasureTime frame
Oxygen saturation;Respiration rate;Endocrine hormones;Blood gas;Visual analog scale;Respiratory quotient;

Countries

China

Contacts

Public ContactWeiqing Wang

Ruijin Hospital, Shanghai Jiaotong University, School of Medicine

wqingw61@163.com+86 18917762201

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026