Post-stroke cognitive impairment
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Aged 50-70 years old; 2. Patients meeting the diagnostic criteria of traditional Chinese and western medicine for ischemic stroke, 2-4 weeks after the occurrence of stroke event; 3. Patients with the first stroke and NIHSS score of 5-15; 4. Patients With cognitive impairment, MoCA score <=26, MMSE score <=26; 5. Patients who were conscious and had no serious aphasia or intelligence disorder, and could communicate normally and complete the scale evaluation; 6. Agree and voluntarily participate in the clinical study, and sign the informed consent.
Exclusion criteria
Exclusion criteria: 1. Patients with diseases related to cognitive impairment, such as epilepsy, Parkinson's disease, Alzheimer's disease, or cognitive impairment prior to stroke events; 2. Accompanied by serious mental diseases such as depression, schizophrenia which may affect the evaluation of cognitive function; 3. Patients with serious heart, liver, kidney, or blood diseases, which are not suitable for the intervention of this study; 4. Auricle malformation, injury, or ulceration, which cannot be interfered with Transcutaneous Auricular Vagus Nerve Stimulation; 5. Electronic devices implanted in the body (such as pacemakers, cochlear implants, etc.); 6. Participating in other clinical trials that conflict with or interact with this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Montreal Cognitive Assessment;Minimum Mental State Examination; | — |
Secondary
| Measure | Time frame |
|---|---|
| Activity of daily living scale;Hamilton anxiety scale; | — |
Countries
China
Contacts
The First Affiliated Hospital of Hunan University of Chinese Medicine