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Effect of peripheral magnetic stimulation on peripheral neuromuscular and brain function in patients with facial paralysis

The effect and mechanism of peripheral magnetic stimulation on patients with facial paralysis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057805
Enrollment
Unknown
Registered
2022-03-17
Start date
2022-03-05
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

facial paralysis

Interventions

Healthy control:Peripheral magnetic stimulation
Stroke without facial paralysis group:Peripheral magnetic stimulation
stroke with facial paralysis group:Peripheral magnetic stimulation

Sponsors

Shanghai Jing'an District Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with cerebral infarction/cerebral hemorrhage confirmed by cranial computed tomography (CT) or magnetic resonance imaging (MRI) (the diagnosis conforms to the consensus of "Main Points of Diagnosis of Various Cerebrovascular Diseases in China 2019" formulated by cerebrovascular Group, Chinese Society of Neurology, Chinese Medical Association); 2. Good cognition, fluent answer, can execute instructions; 3. Age 18-80, primary school education or above; 4. Participate in the study voluntarily and sign informed consent; 5. The onset time at the time of enrollment ranged from 14 days to 6 months; 6. The symptoms are consistent with the manifestations of central facial paralysis after stroke, such as facial motor dysfunction below the unilateral eye cleft.

Exclusion criteria

Exclusion criteria: 1. Previous history of brain trauma, epilepsy, alcohol or drug dependence, and other diseases that may affect brain function and structure; 2. There is a history of peripheral facial paralysis; 3. Alzheimer's disease, Parkinson's disease and other diseases affecting rehabilitation evaluation; 4. Malignant tumor, bleeding tendency, active tuberculosis, severe cardiopulmonary insufficiency and other patients can not tolerate; 5. Congenital facial paralysis patients; 6. Facial trauma and soft tissue contusion occurred within 2 weeks before the experiment; 7. Nearly a week of unilateral facial pain or tooth extraction, orthodontics; 8. There are metal foreign bodies within 30 cm of the treatment site, such as cochlear implant, built-in pulse generator, aneurysm clip, stent, etc.; 9. Patients who participated in other clinical trials of facial rehabilitation or other central interventions (such as transcranial magnetic stimulation and transcranial direct current) at the same time; 10. Severe or recent heart attack; 11. Prior peripheral magnetic stimulation therapy at any part of the body.

Design outcomes

Primary

MeasureTime frame
Blood perfusion;

Secondary

MeasureTime frame
Sunnybrook facial grading system;House-Brackmann grading scale;

Countries

China

Contacts

Public ContactJie Jia

Shanghai Jing'an District Central Hospital

shannonjj@126.com+86 13611722357

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026