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Effect of propofol on postoperative nausea and vomiting after remimazolam combined with alfentanil anesthesia-a randomized control trial

Effect of propofol on postoperative nausea and vomiting after remimazolam combined with alfentanil anesthesia-a randomized control trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057803
Enrollment
Unknown
Registered
2022-03-17
Start date
2022-03-05
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative nausea and vomiting

Interventions

DB group:Dexamethasone 5mg and propofol 20mg
DF group:dexamethasone 5mg and droperidol 1mg
DS group:dexamethasone 5mg and normal saline 2ml

Sponsors

Weifang People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. Elective gynecological hysteroscopic surgery under general anesthesia; 2. ASA1-2 level; 3. BMI 18-24; 4. 18-65 years old.

Exclusion criteria

Exclusion criteria: 1. Patients who are pregnant, breastfeeding, have a history of chronic pain, use of sedatives and analgesics, or are allergic to any drug under study; 2. The operation time is less than 10 minutes or more than 1 hour; 3. Patients discharged the next day; 4. Lack of follow-up of patients.

Design outcomes

Primary

MeasureTime frame
Incidence of nausea and vomiting in PACU;Incidence of nausea and vomiting 24 h after operation;—

Secondary

MeasureTime frame
Severity of nausea and vomiting in PACU;Severity of nausea and vomiting within 24 hours after operation;—

Countries

China

Contacts

Public ContactJi Fanceng

Weifang People's Hospital

jifanceng@163.com+86 13563698838

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026