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The effect of startle-initiated upper limb reach training on motor function in stroke patients

The effect of startle-initiated upper limb reach training on motor function in stroke patients

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057795
Enrollment
Unknown
Registered
2022-03-17
Start date
2022-03-20
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

stroke

Interventions

Experimental group:Upper extremity object-reaching training initiated with sound startle stimuli
Control group:Upper-limb object-reaching training initiated with non-startle sound

Sponsors

Tongji Hospital, Tongji Medical College, Huazhong University of Technology and Science
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-70 years, no gender limit; 2. Within 6 months after the first stroke, the symptoms and imaging diagnosis were clear; 3. Limb motor dysfunction, Fugl-Meyer motor function score <=85, upper limb <=38; 4. Vital signs remain stable for more than 48 hours; 5. The patient has certain cognitive learning ability and can follow simple instructions; 6. The upper limb of the injured side can complete the shoulder forward flexion at least 30 degree; 7. Tolerance to sudden sound stimulation, no obvious discomfort; 8. Sign informed consent and participate in this experiment voluntarily.

Exclusion criteria

Exclusion criteria: 1. Previous history of stroke; 2. Excessive upper/lower limb spasm, modified Ashworth grade 3 or above; 3. Other conditions that significantly affect the function of the upper and lower limbs of the patient, such as joint muscle contracture, severely frozen shoulder, fracture, arthritis, skin ulcers, pressure sores at the treatment site, recent surgical incisions or active skin diseases; 4. Patients with cardiac pacemakers or other implanted electronic devices; 5. Severe cognitive dysfunction, unable to effectively communicate with medical staff; 6. Patients with orthopaedic surgery, rheumatism or other diseases that restrict the movement of the upper and lower limbs; 7. Other conditions (such as severe hypertension, coronary heart disease, etc.) deemed unsuitable by the investigator.

Design outcomes

Primary

MeasureTime frame
Anticipatory muscle activation;Reaching performance scale;

Secondary

MeasureTime frame
Motor evoked potential;Fugel-Meyer motor assessment;

Countries

China

Contacts

Public ContactHuang Xiaolin

Tongji Hospital, Tongji Medical College, Huazhong University

xiaolinh2006@126.com+86 18942942032

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026