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Effect of Esketamine combined with ropivacaine brachial plexus block on postoperative outcome of children with open reduction of humeral fracture

Effect of Esketamine combined with ropivacaine brachial plexus block on postoperative outcome of children with open reduction of humeral fracture

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057774
Enrollment
Unknown
Registered
2022-03-17
Start date
2022-03-15
Completion date
Unknown
Last updated
2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

humeral fracture

Interventions

Group RNS:Mixture of Esketamine and ropivacaine for brachial plexus block
Group RIS:Ropivacaine for brachial plexus block, intravenous Esketamine
Group R:Ropivacaine for brachial plexus block

Sponsors

Anhui Provincial Children's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
2 Years to 10 Years

Inclusion criteria

Inclusion criteria: 1. Patients diagnosed with humeral fracture before surgery and proposed to undergo open reduction; 2. Aged 2-10 years; 3. American Society of Anesthesiologists (ASA) Grades I to II; 4. Obtain the consent of the patient's family before surgery, and sign the informed consent; 5. No analgesics, hormones or any opioids were administered in the 24 hours prior to the operation.

Exclusion criteria

Exclusion criteria: 1. Local anesthetics allergy, puncture site damage, infection, abnormal coagulation function; 2. Allergic to esketamine; 3. Patients with peripheral neuropathy or injury; 4. Patients with severe kidney, liver, neurological or cardiovascular disease.

Design outcomes

Primary

MeasureTime frame
Duration of analgesia;

Secondary

MeasureTime frame
Duration of sensory block;Duration of motor block;The concentrations of cortisol;

Countries

China

Contacts

Public ContactLiu Junxia

Anhui Provincial Children's Hospital

liujunx89@126.com+86 18019995118

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026