postherpetic neuralgia
Conditions
Interventions
acute group:None
chronic phase group:None
control group:None
Sponsors
Sir Run Run Shaw Hospital, School of Medicine, Zhejiang University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Inclusion criteria of the disease group: (1) Patients with herpes zoster in the acute stage (within one month of onset) or chronic stage (over six months of onset); (2) Aged >=18 years; (3) NRS (Pain Numerical Scale) score >=4 points; (4) Sign informed consent. 2. Inclusion criteria of the control group: (1) Healthy people without any other serious diseases; (2) Aged >=18 years;(3) Do not suffer from any form of neuralgia or nerve injury; (4) The score of NRS (Pain Numerical Scale) was between 0 and 1; (5) Sign informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe diseases of the liver or other organs, serious and unstable heart, lung, vascular, gastrointestinal, neurological, endocrine, psychiatric disorders (which may lead to memory impairment, disorientation or inaccurate reporting) or metabolic diseases; ? 2. They have mental disorders that prevent them from correctly evaluating their own conditions, such as the degree of pain, quality of life and adverse reactions; ? ? 3. Patients suffering from cerebral stroke or any other form of cerebrovascular diseases do not have other forms of neuralgia or nerve injury; 4. Diabetic patients; 5. Vulnerable groups, including persons with mental illness, persons with cognitive impairment, critically ill patients, minors, pregnant women, etc.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Blood/Urine metabolomics;Blood/Urine peptidomics;Blood/Urine circRNA;Expression levels of differential metabolites or peptides or circRNAs; | — |
Countries
China
Contacts
Public ContactChen Gang
Outcome results
None listed