Effects of esketamine on retroocular hemodynamics and intracranial pressure

Status

Recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057756

Enrollment

Unknown

Registered

2022-03-16

Start date

2022-03-06

Completion date

Unknown

Last updated

2023-11-13

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

experimental group:Esketamine is given intravenously

control group:Normal saline is injected intravenously

Eligibility

Sex/Gender

All

Age

20 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective surgery, ASA grade I or II; 2. Aged between 20 and 60 years, BMI between 18 and 27 kg /m^2, and duration of surgery between 1 and 3 hours.

Exclusion criteria

Exclusion criteria: 1. Recent severe upper respiratory tract infection, lung infection and other diseases; 2. Preoperative history of intraocular surgery; 3. Identify the difficult airway before surgery; 4. Preoperative symptoms of intraocular hypertension and glaucoma were clearly observed; 5. Preoperative hyperthyroidism, diabetes, hypertension and other serious complications of cardiovascular system; 6. Preoperative administration of iOP drugs; 7. Allergic to narcotic drugs.

Design outcomes

Primary

Measure	Time frame
Rate of blood flow in the posterior artery of the eyeball;Diameter of the optic nerve sheath;	—

Countries

China

Contacts

Public ContactZhang Jianyou

The Affiliated Hospital of Yangzhou University

zhangjianyou@yzu.edu.cn+86 13815813811

Outcome results