Clinical study of different concentration ropivacaine in intercostal nerve block in single-port thoracoscopic lobectomy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057739

Enrollment

Unknown

Registered

2022-03-16

Start date

2022-03-10

Completion date

Unknown

Last updated

2023-11-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

control group:normal saline intercostal nerve block

ropivacaine group 1:2% ropivacaine intercostal nerve block

ropivacaine group 2:3% ropivacaine intercostal nerve block

ropivacaine group 3:4% ropivacaine intercostal nerve block

Eligibility

Sex/Gender

All

Age

40 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Patients undergoing elective single-hole thoracoscopic lobectomy in our hospital during 2021.7-2022.6; 2. Aged 40-75 years; 3. ASA: Grade I-III; 4. Weight 40-90kg.

Exclusion criteria

Exclusion criteria: 1. Patients with contraindications to regional block technique (allergy to local anesthetic, infection around the puncture site and coagulation disorder); 2. Alcohol or drug abuse; 3. Severe circulatory diseases (severe hypertension, bradycardia and other heart diseases); 4. Previous chronic pain; 5. Dysfunction associated with inability to accurately participate in postoperative analgesia evaluation; 6. Active digestive tract ulcers or bleeding; 7. Failure to sign informed consent.

Design outcomes

Primary

Measure	Time frame
First press time of analgesia pump;	—

Secondary

Measure	Time frame
Pain scores at rest and during movement;Number of analgesic pump compressions;Recovery quality score;The amount of remedial drugs used after surgery;Postoperative hospital stay;Postoperative adverse reactions;Intraoperative anesthetic drugs, vasoactive drug dosage and infusion amount;Operation time;Interoperative adverse events;Haemodynamics;Anesthesia time;	—

Countries

China

Contacts

Public ContactXu Guanghong

First Affiliated Hospital of Anhui Medical University

xuguanghong2004@163.com+86 13856949535

Outcome results