None listed
Conditions
Interventions
Experimental group 1:adductor canal block combined with infiltration between the popliteal artery and capsule of the posterior knee
Experimental group 2:adductor canal block combined with oxycodone for intravenous analgesia
Control group:adductor canal block
Sponsors
Xishan People's Hospital of Wuxi
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Patients undergoing unilateral total knee replacement for the first time; 2. In line with the indications of spinal anesthesia; 3. ASA I-?; 4. Aged 18-75 years, gender unlimited; 5. Get informed consent.
Exclusion criteria
Exclusion criteria: 1. Pregnant and lactating patients; 2. Morbid obesity (BMI>=40kg/m^2); 3. Patients with severe heart, brain, liver and kidney diseases; 4. Patients with lower limb paralysis or limb sensory and movement disorders; 5. Patients with mental illness, inability to communicate properly, or inability to correctly score VAS; 6. Patients allergic to amides local anesthetics, opioids and other drugs; 7. Patients with a history of opioid or drug abuse; 8. Patients who failed spinal block and switched to other anesthesia methods; 9. Severe complications such as massive bleeding occurred during the operation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Resting visual analog score;Visual analog score after exercise; | — |
Secondary
| Measure | Time frame |
|---|---|
| Effective pressure times of analgesia pump;Times and total amount of rescue opioids used;Muscle strength of quadriceps femoris;Block of common peroneal nerve;Maximum angle of active flexion of knee joint;Maximum distance of single walking;Serum IL-6;Serum IL-10;Serum C-reactive protein;Adverse events and adverse drug reactions;Patient satisfaction and comfort; | — |
Countries
China
Contacts
Public ContactTang Li
Xishan People's Hospital of Wuxi
Outcome results
None listed