Periodontitis with type 2 diabetes
Conditions
Interventions
Probiotics-Probiotics Group:Probiotics for the first phase and probiotics for the second
Probiotics-Control Group:Probiotics in the first stage and no intervention in the second
Control-Probiotics Group:No intervention was performed in the first phase and probiotics were administered in the second phase
Control-Control Group:None
Sponsors
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Eligibility
Sex/Gender
All
Age
35 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Aged 35-70 years; 2. Diagnosed with type II diabetes mellitus, has been treated for at least 6 months, Hba1c =15 remaining teeth.
Exclusion criteria
Exclusion criteria: 1. Smoking or quitting for less than 5 years; 2. Other systemic diseases known to affect the progression of periodontitis (immune abnormalities, osteoporosis, a history of radiotherapy for the head and neck, etc.); 3. Periodontal treatment within 6 months; 4. Have taken antibiotics, non-steroidal anti-inflammatory drugs, immunosuppressants, hormones and other periodontal drugs within 3 months; 5. Have taken probiotic drugs within 6 months; 6. The need for prophylactic antibiotic use; 7. Pregnant and lactating patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Probing Depth;Microorganism;Gingival Index;Recession Depth;Clinical Attachment Loss;Bleeding of Probing;Fasting Blood Glucose;HbA1c;Gingival Crevicular Fluid IL-1ß, IL-6, TNF-a; | — |
Countries
China
Contacts
Public ContactDing Peihui
The Affiliated Stomatology Hospital of Zhejiang University School of Medicine
Outcome results
None listed