Epidural labor analgesia
Conditions
Interventions
Group 2:0.075% ropivacaine + 0.25mg/ml esketamine
Group 3:0.075% ropivacaine + 0.5mg/ml esketamine
Group 4:0.075% ropivacaine + 0.75mg/ml esketamine
Group 5:0.075% ropivacaine + 1.0mg/ml esketamine
Sponsors
Zhejiang Xiaoshan Hospital
Eligibility
Sex/Gender
Female
Age
18 Years to 40 Years
Inclusion criteria
Inclusion criteria: 1. Maternity aged 18 to 40; 2. ASA Class 1-2; 3. Height = 150 cm, weight = 100 kg; 4. Gestational age = 37 weeks; 5. Head position; 6. Cervical dilatation 3-7cm; 7. VAS = 30mm (0=no pain, 100=most painful).
Exclusion criteria
Exclusion criteria: 1. Intraspinal anesthesia contraindication; 2. People who are allergic to anesthetics and Esketamine; 3. Bradycardia; 4. Multiple pregnancy; 5. Preeclampsia; 6. Fetal abnormality; 7. Those who refuse to sign the informed consent form; 8. Other information: history of cesarean section, and parturients who have used sedatives or analgesics for a long time.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The effective rate of labor analgesia after 30 minutes of epidural loading.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Maternal basic information;NRS (before analgesia, 30min, 60min, uterine opening, fetal delivery);Time of labor;Basic vital signs of parturient women;Use of anesthetic drugs after placenta delivery;Total press times of PCEA and effective press times;Mode of delivery;side effect;Neonatal outcome; | — |
Countries
China
Contacts
Public ContactZhong Mei
Zhejiang Xiaoshan Hospital
Outcome results
None listed