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Multicenter, prospective real-world study of the efficacy and safety of a comprehensive treatment regimen based on TAS-102 for metastatic colorectal cancer

Multicenter, prospective real-world study of the efficacy and safety of a comprehensive treatment regimen based on TAS-102 for metastatic colorectal cancer

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057659
Enrollment
Unknown
Registered
2022-03-15
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-03-06

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Metastatic colorectal cancer

Interventions

Case series:TAS-102

Sponsors

Jiangsu Provincial People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Age = 18 years, regardless of gender; 2. Patients with metastatic colorectal cancer (mCRC) at all stages confirmed by histopathology, cytology and imaging data; 3. According to the doctor's judgment, it is suitable to receive the comprehensive treatment based on TAS-102; 4. Good compliance and voluntary signing of informed consent.

Exclusion criteria

Exclusion criteria: 1.Have a serious underlying medical condition that makes it impossible to safely administer trial treatment. Including, but not limited to, active infections requiring systemic therapy: decompensated heart failure (NYHA classification III and IV), unstable angina, acute myocardial infarction and other diseases within 1 month before admission; 2.Other reasons that the researcher determines are not suitable for participating in this study.

Design outcomes

Primary

MeasureTime frame
Median progression free survival;

Secondary

MeasureTime frame
1-year overall survival rate;Objective remission rate;Disease control rate;Duration of remission;Time to disease progression;Changes of tumor related markers;Security;1-year median progression free survival;

Countries

China

Contacts

Public ContactGu Yanhong

Department of Oncology, Jiangsu Provincial People's Hospital

guluer@163.com+86 13813908678

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026