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Effects of low-concentration atropine use frequency on children's myopia control and ocular biological parameters

Effects of low-concentration atropine use frequency on children's myopia control and ocular biological parameters

Status
Active, not recruiting
Phases
Phase 3
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057647
Enrollment
Unknown
Registered
2022-03-15
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

myopia

Interventions

Group 1 :0.01% atropine eye drop OU QN
Group 2:0.01% atropine eye drop OU TID

Sponsors

Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
6 Years to 9 Years

Inclusion criteria

Inclusion criteria: 1. Children aged 6-9 years; 2. Low myopia: -0.50D <= diopter < -3.00D; 3. Astigmatism less than 1.50D; 4. No other eye diseases and keratoconus except ametropia; 5. Intraocular pressure within normal range ( < 21 mmHg); 6. Optimal corrected vision is 1.0.

Exclusion criteria

Exclusion criteria: 1. Patients with abnormal binocular vision; 2. Have a history of wearing contact lenses or using drugs that may affect the development of myopia; 3. Ocular surface diseases and other ocular diseases causing ocular surface abnormalities; 4. History of eye trauma and surgery.

Design outcomes

Primary

MeasureTime frame
axial length;

Secondary

MeasureTime frame
refraction;corneal morphology;aberrations;peripheral refraction;tear quality;corneal biomechanical parameters;objective scatter index;choroidal thickness;pupil diameter;accommodation function;intraocular pressure;

Countries

China

Contacts

Public ContactMengjun Zhu

Shanghai Eye Disease Prevention & Treatment Center/Shanghai Eye Hospital

morning5012@163.com+86 13818102138

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026