Acute respiratory distress syndrome
Conditions
Interventions
Group 1 :
Sponsors
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. 18 years < age < 80 years; 2. Diagnosed as moderate or severe ARDS according to the Berlin 2014 definition; 3. Predicted APRV mechanical ventilation for more than 72 hours.
Exclusion criteria
Exclusion criteria: 1. APRV contraindications such as pneumothorax, severe COPD, severe asthma, intracranial hypertension; 2. Pregnant women; 3. Severe cardiac dysfunction (New York Heart Association Class ? or ?, acute coronary syndrome or persistent ventricular tachyarrhythmia), chronic cardiopulmonary disease resulting in right heart enlargement, cardiogenic shock, etc.; 4. Refractory shock 5. BMI > 35 kg/m2.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Gas distribution in the lungs; | — |
Secondary
| Measure | Time frame |
|---|---|
| Gas distribution in the lungs;Intrapulmonary shunt;respiratory mechanics;Cardiac function index;hemodynamic parameters;Arterial blood gas analysis;Sequential Organ Failure Assessment score;Acute Physiology and Chronic Health Evaluation score; | — |
Countries
China
Contacts
Public ContactXiaojing Zou
Union Hospital, Tongji Medical College, Huazhong University of Science and Technology
Outcome results
None listed