Metabolic syndrome and prostate disease
Conditions
Interventions
Simple BPH group:
Simple MetS group:
BPH and MetS group:
Normal group:
Sponsors
Affiliated Hospital of Zunyi Medical University
Eligibility
Sex/Gender
Male
Age
45 Years to 90 Years
Inclusion criteria
Inclusion criteria: 1. Consistent with metabolic syndrome diagnosis: (1) Patients who present at least three of the following five risk factors are considered to have MetS: 1) Abdominal obesity (male waist > 90 cm, female waist > 85 cm); 2) High triglyceride (TG >= 1.70 mmol/L); 3) Low high density lipoprotein cholesterol (HDL-C 130/85 mmHg); 5) High fasting blood glucose (FPG > 6.10 mmol/L); 2. The patient was clinically diagnosed as benign prostatic hyperplasia.
Exclusion criteria
Exclusion criteria: 1. Participants with a history of prostate or urethral surgery; 2. Patients with urethral stricture, urinary tract infection, malignant tumor or neurogenic bladder; 3. Long-term users of anticholinergics, 5-reductase inhibitors, phosphodiesterase inhibitors and hormone replacement therapy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Total prostate volume;Total testosterone;Estradiol;Sex hormone binding globulin;Dihydrotestosterone;Insulin; | — |
Secondary
| Measure | Time frame |
|---|---|
| Age;Body mass index;Waistline;Systolic pressure;Diastolic blood pressure;Blood glucose;Triglyceride;High-density lipoprotein cholesterol;Low density lipoprotein cholesterol;Total cholesterol;International Prostate Symptom Scale;Urination period;Quality of life score;Prostate specific antigen;Maximum urinary flow rate; | — |
Countries
China
Contacts
Public ContactChen Zongping
Affiliated Hospital of Zunyi Medical University
Outcome results
None listed