Effects of quadratus lumbosum block on inflammatory stress response and postoperative intestinal function in patients undergoing laparoscopic colorectal cancer

Status

Active, not recruiting

Phases

Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057628

Enrollment

Unknown

Registered

2022-03-15

Start date

2022-03-01

Completion date

Unknown

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

colorectal cancer

Interventions

Group A:Simple general anesthesia

Group B:QLB combined with general anesthesia

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: 1. ASA I-II; 2. Age 18-65 years; 3. Patients undergoing elective laparoscopic colorectal cancer surgery.

Exclusion criteria

Exclusion criteria: 1. BMI > 30 kg/m2; 2. Allergic to local anesthetic drugs; 3. Patients with malnutrition, abnormal coagulation and preoperative chemotherapy; 4. Patients with with serious cardiovascular disease, diabetes and metabolic syndrome; 5. Patients with local or systemic inflammatory diseases and long-term use of NSAIDs; 6. Abnormal liver and kidney function; 7. Steroid or immunosuppressant user; 8. People with hearing impairment or psycho-nervous system diseases.

Design outcomes

Primary

Measure	Time frame
Tumor necrosis factor-alpha, TNF-a;Interleukin-6, IL-6;Interleukin-10, IL-10;Postoperative intestinal function recovery time;Feeding time;The incidence and extent of abdominal distention;	—

Countries

China

Contacts

Public ContactNingkang Li

People's Hospital of Ningxia Hui Autonomous Region

13629577087@163.com+86 13629577087

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026