Chronic Obstructive Pulmonary Disease
Conditions
Interventions
Basic treatment group:
Basic treatment and Broncho-Vaxom group:
Sponsors
Shandong Provincial Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years; 2. It meets the diagnostic criteria of 2022 gold COPD: after using bronchodilator, the ratio of forced expiratory volume in the first second to forced vital capacity (FEV1:FVC) is less than 0.70; 3. Informed consent must be signed before being included in the cohort, and participate in the study protocol and follow-up according to the protocol.
Exclusion criteria
Exclusion criteria: 1. Suffering from severe pleural disease and/or sternal and rib lesions; 2. Suffering from serious cardiovascular disease, liver and kidney dysfunction, cancer and other uncontrolled systemic diseases; 3. Previous alcoholism, drug abuse, drug abuse or organic solvent abuse, or poor compliance such as mental illness, epilepsy or other central nervous system diseases, or any other situation interfering with clinical trials; 4. Women of childbearing age who are currently pregnant or lactating; 5. Researchers who received immunosuppressive therapy or participated in other clinical trials 3 months before enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Demographic data;Basic vital signs;routine blood test;C-reactive protein;Procalcitonin;Immunoglobulin E;liver function;Blood biochemistry;12 cytokines;Bacteriological index;Pulmonary function test;Chest computerized tomography;Evaluation scale; | — |
Countries
China
Contacts
Public ContactLin Dianjie
Shandong Provincial Hospital
Outcome results
None listed