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A clinical study on the effect of three ovulation induction programs including double ovulation induction program, antagonist regimen and mild stimulation scheme in the patients with diminished ovarian reserve

A clinical study on the effect of three ovulation induction programs including double ovulation induction program, antagonist regimen and mild stimulation scheme in the patients with diminished ovarian reserve

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057609
Enrollment
Unknown
Registered
2022-03-15
Start date
2022-03-12
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

double ovulation induction group:double ovulation induction
antagonist regimen group:antagonist regimen
mild stimulation group:mild stimulation scheme

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 48 Years

Inclusion criteria

Inclusion criteria: 1. Basal follicle stimulating hormone (Bfsh) >= 10 U/L or FSH/LH > 3; 2. Transvaginal B-ultrasound suggested bilateral ovarian sinus follicles (AFC) <= 7; 3. Low ovarian response in previous cycles; no more than 3 eggs were obtained in conventional plan.

Exclusion criteria

Exclusion criteria: 1. If one or both couples have chromosomal abnormalities, PGT-SR or PGT-M is required; 2. Abnormal reproductive tract anatomy, such as mediastinum, single horned uterus, etc.; 3. Endocrine abnormalities 4. Abnormal immunological examination 5. Prethrombotic state, such as abnormal anticardiolipin antibody, abnormal protein S, protein C, etc.; 6. Reproductive tract infection; 7. The male suffers from retrograde ejaculation disease, severe oligospermia or azoospermia and needs epididymis or testicular puncture; 8. There are high risk factors for abortion such as toxic chemicals in the living environment; 9. Associated diseases affecting IVF pregnancy outcome, such as severe adenomyosis, untreated hydrosalpinx, untreated endometrial lesions, uterine fibroids >= 4 cm, etc.; 10. Other ART contraindications and serious systemic diseases.

Design outcomes

Primary

MeasureTime frame
High-quality embryos rate;Numbers of retrieved oocytes;

Countries

China

Contacts

Public ContactYang Yizhuo

Chinese PLA General Hospital

estroe@sina.com+86 13522707077

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026