A comparative study on the effect of anesthesia with esmketamine or fentanyl combined with propofol on respiration in abortion/curettage

The effect of anesthesia with esmketamine or fentanyl combined with propofol on respiration in patients undergoing abortion or curettage:a prospective, double-blinded, randomized and placebo-controlled clinical trial

Status

Active, not recruiting

Phases

Phase 4

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057602

Enrollment

Unknown

Registered

2022-03-15

Start date

2022-03-18

Completion date

Unknown

Last updated

2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Anesthesiology

Interventions

Group 1 :Fentanyl

Group 2:Esketamine

Eligibility

Sex/Gender

Female

Age

18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-60 years; 2. ASA I-II class.

Exclusion criteria

Exclusion criteria: 1. Insufficiency of liver and kidney function; 2. Allergic to the drug under study; 3. Patients with neurological or cardiovascular diseases; 4. Obesity; 5. Difficult airway; 6. Take pain relief; 7. Severe hypertension; 8. Pulmonary heart disease; 9. Pulmonary arterial hypertension; 10. Increased intracranial pressure; 11. High intraocular pressure; 12. Cardiac insufficiency; 13. Hyperthyroidism; 14. Patients with epilepsy and psychosis.

Design outcomes

Primary

Measure	Time frame
Incidence of hypoxemia;	—

Secondary

Measure	Time frame
Vital signs;	—

Countries

China

Contacts

Public ContactXuehai Guan

The First Affiliated Hospital of Guangxi Medical University

guan_xh@aliyun.com+86 18587697310

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026