Postoperative recovery
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Age >= 60 years old; 2. American Society of Anesthesiologists (ASA) physical status I-III; 3. Scheduled for elective major laparoscopic gastrointestinal surgery under general anesthesia (duration of surgery >=2 h); 4. Provision of written informed consent.
Exclusion criteria
Exclusion criteria: 1. Severe cardiopulmonary disease; 2. Severe cerebrovascular disease; 3. Severe hepatic or renal disease (Child-Pugh C or renal replacement therapy); 4. Neurological or psychiatric disease; 5. Preoperative Mini-mental State Examination (MMSE) scores <= 23; 6. Visual and hearing impairment; 7. Inability to cooperate or complete the study questionnaires.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative recovery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative delirium;length of PACU stay;Time to extubation;Length of hospital stay;In-hospital mortality;Complications (myocardial infarction, cardiac arrest, arrhythmia, cardiac insufficiency, respiratory failure, pulmonary embolism, renal insufficiency, sepsis, wound infection);30-day mortality;Postoperative recovery;Incidence of hypotension;Duration of hypotension;Use of vasopressors; | — |
Countries
China
Contacts
The First Affiliated Hospital of Soochow University