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Effects of deep versus light anesthesia under mornitoring of regional cerebral oxygenation and bispectral index on postoperative recovery of elderly patients after major laparoscopic gastrointestinal surgery: a randomized controlled trial

Effects of deep versus light anesthesia under mornitoring of regional cerebral oxygenation and bispectral index on postoperative recovery of elderly patients after major laparoscopic gastrointestinal surgery: a randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057597
Enrollment
Unknown
Registered
2022-03-15
Start date
2022-03-21
Completion date
Unknown
Last updated
2023-10-30

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative recovery

Interventions

Light anesthesia:BIS target 50-55
Deep anesthesia:BIS target 35-40

Sponsors

The First Affiliated Hospital of Soochow University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
60 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age >= 60 years old; 2. American Society of Anesthesiologists (ASA) physical status I-III; 3. Scheduled for elective major laparoscopic gastrointestinal surgery under general anesthesia (duration of surgery >=2 h); 4. Provision of written informed consent.

Exclusion criteria

Exclusion criteria: 1. Severe cardiopulmonary disease; 2. Severe cerebrovascular disease; 3. Severe hepatic or renal disease (Child-Pugh C or renal replacement therapy); 4. Neurological or psychiatric disease; 5. Preoperative Mini-mental State Examination (MMSE) scores <= 23; 6. Visual and hearing impairment; 7. Inability to cooperate or complete the study questionnaires.

Design outcomes

Primary

MeasureTime frame
Postoperative recovery;

Secondary

MeasureTime frame
Postoperative delirium;length of PACU stay;Time to extubation;Length of hospital stay;In-hospital mortality;Complications (myocardial infarction, cardiac arrest, arrhythmia, cardiac insufficiency, respiratory failure, pulmonary embolism, renal insufficiency, sepsis, wound infection);30-day mortality;Postoperative recovery;Incidence of hypotension;Duration of hypotension;Use of vasopressors;

Countries

China

Contacts

Public ContactPeng Ke

The First Affiliated Hospital of Soochow University

pengke0422@163.com+86 0512-67780055

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026