postoperative depression
Conditions
Interventions
Experiment group:S-Ketamine
Control group:Sufentanil
Sponsors
Qingdao Municipal Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age from 18 to 75 years old, regardless of gender; 2. ASA grade I to III; 3. BMI >= 19 and <= 30 kg/m2; 4. Pathologically diagnosed as colon/rectal cancer; 5. No cancer cells have spread or metastasized far away; 6. Non-emergency inpatients who have undergone routine preoperative preparation; 7. Volunteer to participate in this study and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1. History of mental illness or being treated with psychotropic drugs; 2. History of drug, alcohol or opioid abuse; 3. Being treated with monoamine oxidase (MAO) inhibitors; 4. Taking other experimental drugs or participating in other clinical trials 3 months before being selected for the study; 5. People with severe heart, brain, lung, liver, kidney and hematopoietic system diseases; 6. People with allergies and allergies to opioids, tramadol and ketamine; 7. Women during pregnancy and lactation; 8. Unable to cooperate with the research for any reason.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Beck Depression Inventory;Beck Anxiety Inventory; | — |
Secondary
| Measure | Time frame |
|---|---|
| Visual Anoalogue Scale;Patient Controlled Intravenous Analgesia counts; | — |
Countries
China
Contacts
Public ContactLixin Sun
Qingdao Municipal Hospital
Outcome results
None listed