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Effect of propofol-remifentanil versus propofol-etomidate remifentanil on patients undergoing painless digestive endoscopy: a randomized controlled trial

Effect of propofol-remifentanil versus propofol-etomidate remifentanil on patients undergoing painless digestive endoscopy: a randomized controlled trial

Status
Recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057519
Enrollment
Unknown
Registered
2022-03-14
Start date
2022-03-15
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastrointestinal disease

Interventions

Experimental group:Propofol (1mg/kg)- etomidate (0.2mg/kg)- remifentanil (0.2ug/kg)
Control group:Propofol (2mg/kg)- remifentanil (0.2ug/kg)

Sponsors

The First Affiliated Hospital of Anhui Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. American Society of Anesthesiologists (ASA) Grade I-III. 2. Fast for at least 8 hours, last drink laxatives for at least 4 hours, no water for at least 2 hours. 3. Aged 18-70 years. 4. Have hypertension, diabetes, hyperlipidemia, hepatitis B and other chronic diseases, but take drugs to control well, no abnormal liver and kidney function, stable hemodynamics.

Exclusion criteria

Exclusion criteria: 1. Patients with severe cardiovascular disease, hemodynamic instability, glaucoma, elevated intracranial pressure, psychosis, nervous system disease, vomiting, hormone drug use, and adrenal dysfunction. 2. Known allergy to any study medication and refusal by the patient himself or an authorized relative.

Design outcomes

Primary

MeasureTime frame
Blood pressure and heart rate;Oxygen saturation;Additional dose;Patient satisfaction;

Countries

China

Contacts

Public ContactLu Xianfu

The First Affiliated Hospital of Anhui Medical University

ahluxianfu@163.com+86 18256031820

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026