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The role and therapeutic potentiation of gut microbiome in alcohol use disorder

The role and therapeutic potentiation of gut microbiome in alcohol use disorder

Status
Active, not recruiting
Phases
Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057517
Enrollment
Unknown
Registered
2022-03-14
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Alcohol use related disorders

Interventions

Han alcohol use disorder group:None
Han healthy control group:None
Uygur alcohol use disorder group:None
Uygur healthy control group:None

Sponsors

The Second Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Male
Age
25 Years to 55 Years

Inclusion criteria

Inclusion criteria: 1. Male aged 25-55 years. 2. Alcohol Dependence group: Patients with alcohol dependence were assessed according to the Alcohol Use Disorders Screening Scale (AUDIT) with a total score of 20 or more. 3. Healthy control group: Age basically matched with case group.

Exclusion criteria

Exclusion criteria: 1. Diabetes mellitus, irritable bowel syndrome, and inflammatory bowel disease in the year before the study; 2. Abusers of substances other than tobacco and patients suffering from depression and other mental disorders; 3. Those who have used probiotics, prebiotics, probiotics and prebiotic mixtures and antibiotics in the month prior to the collection of stool, and those who are known to be infected with bacteria, molds and viruses in the acute phase.

Design outcomes

Primary

MeasureTime frame
Severity of alcohol dependence;Severity of depressive symptoms;Liver function;

Countries

China

Contacts

Public ContactZhang Xiaojie; Hao Wei

The Second Xiangya Hospital, Central South University

xiaojiezhang2014@csu.edu.cn+86 15874919211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026