Hypotension after induction of anesthesia
Conditions
Interventions
Crystal group:Compound sodium chloride injection 6ml/kg was given 10min after endotracheal intubation and was rapidly injected intravenously within 15min
Colloid group:10min after endotracheal intubation was established, succinyl gelatin injection 6ml/kg was administered intravenously within 15min
Control group:After entering the room, an intravenous channel was established and 10ml/kg/h sodium lactate Ringer Solution was administered intravenously
Sponsors
Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Patients who are scheduled to undergo surgery under endotracheal intubation and general anesthesia; 2. ASA grade I - II; 3. Aged between 18 and 65; 4. Body mass index (BMI) 15-30kg /m^2; 5. No mental illness or cognitive impairment.
Exclusion criteria
Exclusion criteria: 1. Those who refuse ultrasonic monitoring and examination; 2. Patients with difficulty in airway or endotracheal intubation; 3. Patients who need to adopt protective lung ventilation strategy; Carotid artery anatomic malformation, atherosclerosis, stenosis, thrombosis or cervical surgery; 4. Patients with other severe peripheral vascular diseases or intracranial hypertension; 5. Preoperative uncontrolled hypertension; Recent use of hypertensive drugs; 6. Severe organ dysfunction of liver and kidney (e.g., blood creatinine and liver enzyme > 2 times the normal clinical limit); 7. Patients with cardiac insufficiency (EF < 45%), pulmonary hypertension or above moderate valvular disease; 8. Patients with cardiac pacemaker implantation and atrial fibrillation and other arrhythmias; 9. Severe anemia; 10. There are known studies involving drug or colloid allergy; 11. Emergency operation patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid artery corrected ejection time;Common carotid artery peak velocity variation;Average peak flow velocity of common carotid artery; | — |
Countries
China
Contacts
Public ContactLi Guocai
Shenzhen Hospital (Futian) of Guangzhou University of Chinese Medicine (Futian)
Outcome results
None listed