Clinical effect of nalbuphine as an adjuvant to ropivacaine in ultrasound-guided erector spinal plane block on postoperative analgesia in patients undergoing percutaneous nephroscopy

Status

Active, not recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057493

Enrollment

Unknown

Registered

2022-03-14

Start date

2022-04-01

Completion date

Unknown

Last updated

2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

None listed

Interventions

Group R:patients received a unilateral ultrasound-guided ESP block with ropivacaine 0.33% at T10 level

Group RNL:patients received a unilateral ultrasound-guided ESP block with 0.33% ropivacaine + 2 ml of 10 mg nalbuphine at T10 level

Group RNH:patients received a unilateral ultrasound-guided ESP block with 0.33% ropivacaine + 2 ml of 20 mg nalbuphine at T10 level

Eligibility

Sex/Gender

All

Age

18 Years to 65 Years

Inclusion criteria

Inclusion criteria: American Society of Anesthesiologists (ASA) Class I-II, aged 18-65 years, undergoing elective unilateral percutaneous nephrolithotomy at our hospital.

Exclusion criteria

Exclusion criteria: Unable to cooperate, allergic to local anesthesia drugs, chronic analgesia history, BMI>35, skin infection at the injection site.

Design outcomes

Primary

Measure	Time frame
visual analogue scale score;	—

Secondary

Measure	Time frame
consumption of propofol during surgery;consumption of remifentanil during surgery;time of first opiate infusion with analgesic pump;time (minutes) from arrival at PACU to first landing (i.e. until being able to stand and walk unaided);the number of self-controlled analgesia compressions within 24 hours after surgery;rescue analgesia requirement in the 24 h postoperative period;length of hospital stay;the occurrence of adverse reactions such as nausea and vomiting within 24 hours after surgery;	—

Measure

Time frame

consumption of propofol during surgery;consumption of remifentanil during surgery;time of first opiate infusion with analgesic pump;time (minutes) from arrival at PACU to first landing (i.e. until being able to stand and walk unaided);the number of self-controlled analgesia compressions within 24 hours after surgery;rescue analgesia requirement in the 24 h postoperative period;length of hospital stay;the occurrence of adverse reactions such as nausea and vomiting within 24 hours after surgery;

—

Countries

China

Contacts

Public ContactWang Tingting

Union Hospital Affiliated to Tongji Medical College, Huazhong University of Science and Technology

wangtt201307@163.com+86 13667265360

Outcome results