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A preliminary study on the evaluation of endometrial receptivity by plasma exosome transcriptome

A preliminary study on the evaluation of endometrial receptivity by plasma exosome transcriptome

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057492
Enrollment
Unknown
Registered
2022-03-14
Start date
2022-03-01
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

infertility

Interventions

Gold Standard:Pregnancy endometrial histological scanning electron microscopy, endometrial ultrasonography, blood endocrine hormone detection.
Index test:Endometrial receptivity test RNA sequencing.

Sponsors

Reproductive Medicine Center of Xiangya Hospital, Central South University
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
20 Years to 39 Years

Inclusion criteria

Inclusion criteria: 1. Aged between 20 and 39; 2. BMI 18-25 kg/m^2; 3. Regular menstrual cycle (25-35 days) with spontaneous ovulation; 4. The ovarian reserve function was normal (basal FSH1.5ng/ml, sinus follicle number > 5); 5. Patients with natural cycle frozen embryo transplantation or ovulation monitoring.

Exclusion criteria

Exclusion criteria: 1. Patients with endometrial lesions (including endometrial adhesion, endometrial polyps, endometrial tuberculosis, etc.); 2. Patients with hydrosalpinx without proximal tubal ligation; 3. Patients with submucosal uterine fibroids or intramural uterine fibroids or adenomyomas protruding into the uterine cavity; 4. Patients with endometriosis (stage III -- IV); 5. Patients with uterine malformations.

Design outcomes

Primary

MeasureTime frame
mRNA;

Countries

China

Contacts

Public ContactLi Yanping
liyanp@csu.edu.cn+86 13607317798

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026