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Study on the registration of intracranial atherosclerotic stenosis

Study on the registration of intracranial atherosclerotic stenosis

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2200057482
Enrollment
Unknown
Registered
2022-03-13
Start date
2022-04-16
Completion date
Unknown
Last updated
2023-10-22

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cerebrovascular disease

Interventions

case series:None

Sponsors

Ji'ning First People's Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 85 Years

Inclusion criteria

Inclusion criteria: 1. Aged 18-85 years, no gender limit. 2. Craniocerebral magnetic imaging (MRA), CT angiography (CTA), and cerebrovascular angiography (DSA) of the patient showed intracranial great blood vessel stenosis or occlusion, and it was the responsible blood vessel of intracranial ischemic lesion. The selected intracranial great blood vessels included: intracranial segment of internal carotid artery (ICA), middle cerebral artery M1 (MCA), anterior cerebral artery A1 (ACA), vertebral artery intracranial segment (VA), posterior cerebral artery P1 (PCA), and basilar artery (BA). 3. The patient was a first-time patient with NIHSS score <22, or had a history of cerebral infarction with NIHSS score < 4. 4. Informed consent of patients or family members to treatment.

Exclusion criteria

Exclusion criteria: 1. Patients with obvious heart, liver, kidney and lung failure. 2. Patients with severe gastrointestinal disease or history of gastrointestinal surgery may be affected by drug absorption. 3. Accompanied by epilepsy symptoms. 4. Patients with adverse reactions to atorvastatin, probuco, butylphthalide capsule, Tongxinluo soft capsule and cilostazole. 5. With severe systemic disease that significantly reduces life expectancy. 6. Patients enrolled in other clinical trials. 7. Patients with dysphagia dysfunction and inability to take drugs orally. 8. MRS Score >=3 points.

Design outcomes

Primary

MeasureTime frame
Degree of intracranial artery stenosis;Stroke recurrence;

Countries

China

Contacts

Public ContactLiu Huakun

Ji'ning First People's Hospital

woshiliuhuakun@163.com+86 15020780736

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026