acute ischemic stroke
Conditions
Interventions
case series:None
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 79 Years
Inclusion criteria
Inclusion criteria: 1. Aged between 18 and 79 years; 2. Occlusion of anterior circulation great vessels; 3. Vascular recanalization was performed within 6 hours or 6-24 hours after onset and imaging findings were consistent with DAWN and DEFUSE3 thrombectomy indications; 4. The patient or family member understands and has signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. The patient has a history of intracranial hemorrhage in the last 3 weeks, and has been found to have cerebral arteriovenous malformation or aneurysm without intervention or surgical treatment; 2. Refractory hypertension that cannot be controlled by medication (systolic blood pressure >185mmHg, or diastolic blood pressure >110mmHg); 3. Known allergy to contrast media; 4. Blood glucose 22.0 mmol/L; 5. Acute bleeding constitution, including coagulation factor deficiency disease, INR>1.7 or platelet count <100x10^9/L; 6. Patients with left ventricular ejection fraction < 50% or heart failure; 7. Severe stenosis or occlusion of the contralateral carotid artery, vertebrobasilar artery and other intracranial arteries (more than 50%); 8. Failed to complete the fNIRS check; 9. Severe depression, mental illness, epilepsy.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin score (mRS); | — |
Secondary
| Measure | Time frame |
|---|---|
| Changes in brain function; | — |
Countries
China
Contacts
Public ContactZhao Fei
Shanghai Sixth People's Hospital
Outcome results
None listed