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Effect of prehabilitation-related dietary protein intake on quality of recovery after elective cardiac surgery: a randomized controlled trial

Effect of prehabilitation-related dietary protein intake on quality of recovery after elective cardiac surgery: a randomized controlled trial

Status
Recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2200057463
Enrollment
Unknown
Registered
2022-03-13
Start date
2022-09-01
Completion date
Unknown
Last updated
2024-07-08

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

preoperative protein-calorie malnutrition

Interventions

Sponsors

Department of Anesthesia and Intensive Care, The Chinese University of Hong Kong
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 100 Years

Inclusion criteria

Inclusion criteria: 1. Adults (no age restriction) undergoing elective or non-emergent major to ultra-major cardiac surgery (CABG, valve surgery or combined) 2. MUST>0 or FFMI<17 for men or FFMI<15 for women or SMI<7 for men or SMI<5.7 for women Patients on the elective cardiac surgery waiting list are routinely assessed the Perioperative Medicine Clinic several weeks before the scheduled operation date. After written informed consent, patients will complete the MUST questionnaire and undertake a body composition test using a bioelectrical impedance analysis device (InBody 270, InBodyUSA, Cerritos, CA) to measure FFMI and SMI for study eligibility determination.

Exclusion criteria

Exclusion criteria: 1. Redo or emergency cardiac surgery 2. Major comorbidities precluding surgery, are mentally incompetent, any current disorder impairing accurate and objective completion of the malnutrition assessment and questionnaires, or are unable to understand Chinese or English. 3. CKD not on dialysis requiring low protein diet, advanced stage CKD or end-stage renal disease on dialysis with protein requirements of 1.0 to 1.2 g/kg body weight/day will be excluded [38] 4. Patients with liver diseases and at risk for hepatic encephalopathy 5. Physical limitations that would preclude regular attendance to outpatient nutritional prehabilitation sessions 6. Seen by a dietician in the last 6 months

Design outcomes

Primary

MeasureTime frame
quality of recovery;Days (alive and) at home within 30 (DAH30) days after cardiac surgery;

Secondary

MeasureTime frame
Disability-free survival at 30 after surgery ;Health-related quality of life;Cardiac Postoperative Morbidity Survey (C-POM);

Countries

China

Contacts

Public ContactProfessor Anna Lee

The Chinese University of Hong Kong

annalee@cuhk.edu.hk+852 35052739

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 9, 2026