Functional near-infrared spectroscopy-based study of transcranial direct current stimulation to improve post-stroke cognitive impairment and its brain remodeling mechanism

Status

Recruiting

Phases

Early Phase 1

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2200057449

Enrollment

Unknown

Registered

2022-03-12

Start date

2022-03-01

Completion date

Unknown

Last updated

2023-10-16

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

post-stroke cognitive impairment

Interventions

Group A:True Stimulation

Group B:Shame Stimulation

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Aged from 30 to 75 years old, with initial onset and stable vital signs; 2. Course of disease = 6 months; 3. The score of Mini mental State Examination (MMSE) is = 24; And cognitive impairment occurred after stroke, and other causes were excluded; 4. Native language is Chinese, and can cooperate in completing the test; 5. Right handed; 6. Voluntary participation and signing of informed consent.

Exclusion criteria

Exclusion criteria: 1. Equipped with cardiac pacemaker or metal implants in the skull; 2. Local skin is damaged or inflamed; 3. There is fever, electrolyte disorder or unstable vital signs; 4. Have a history of seizures; 5. Increased intracranial pressure; 6. Complicated with serious heart disease, liver and kidney failure, malignant tumor, gastrointestinal bleeding and other diseases can not cooperate to complete the treatment.

Design outcomes

Primary

Measure	Time frame
Mini-Mental State Examination;	—

Secondary

Measure	Time frame
Montreal Cognitive Assessment;the Barthelindex of ADL;	—

Countries

China

Contacts

Public ContactSongmei Chen

Shanghai No.3 Rehabilitation Hospital

18117517656@163.com+86 18117517656

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026